Human apolipoprotein A-I natural variants: molecular mechanisms underlying amyloidogenic propensity.

Human apolipoprotein A-I natural variants: molecular mechanisms underlying amyloidogenic propensity.

Human apolipoprotein A-I (apoA-I)-derived amyloidosis can present with either wild-type (Wt) protein deposits in atherosclerotic plaques or as a hereditary form in which apoA-I variants deposit causing multiple organ failure. More than 15 single amino acid replacement amyloidogenic apoA-I variants h...

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Bibliographic Details
Main Authors: Nahuel A Ramella, Guillermo R Schinella, Sergio T Ferreira, Eduardo D Prieto, María E Vela, José Luis Ríos, M Alejandra Tricerri, Omar J Rimoldi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3429494?pdf=render

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http://europepmc.org/articles/PMC3429494?pdf=render

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