The effects of immunization with recombinant Sm14 (rSm14) in reducing worm burden and mortality of mice infected with Schistosoma mansoni

The effects of immunization with recombinant Sm14 (rSm14) in reducing worm burden and mortality of mice infected with Schistosoma mansoni

To investigate whether mice immunization with the recombinant form of a 14.7 KDa Schistosoma mansoni protein (rSm14) confers protection against a S. mansoni lethal challenge infection, rSm14-immunized mice were challenged with different cercarial burdens. A significant protection was detected in imm...

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Bibliographic Details
Main Authors: Fábio Ribeiro, Cristiane dos Santos Vieira, Adriana Fernandes, Neusa Araújo, Naftale Katz
Format: Article
Language:English
Published: Sociedade Brasileira de Medicina Tropical (SBMT) 2002-02-01
Series:Revista da Sociedade Brasileira de Medicina Tropical
Subjects:
Schistosoma mansoni
recombinant Sm14
Immunization
Fatty acid binding protein
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822002000100003&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822002000100003&tlng=en

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