Bayesian workflow for the investigation of hierarchical classification models from tau-PET and structural MRI data across the Alzheimer’s disease spectrum

Bayesian workflow for the investigation of hierarchical classification models from tau-PET and structural MRI data across the Alzheimer’s disease spectrum

BackgroundAlzheimer’s disease (AD) diagnosis in its early stages remains difficult with current diagnostic approaches. Though tau neurofibrillary tangles (NFTs) generally follow the stereotypical pattern described by the Braak staging scheme, the network degeneration hypothesis (NDH) has suggested t...

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Bibliographic Details
Main Authors: Clyde J. Belasso, Zhengchen Cai, Gleb Bezgin, Tharick Pascoal, Jenna Stevenson, Nesrine Rahmouni, Cécile Tissot, Firoza Lussier, Pedro Rosa-Neto, Jean-Paul Soucy, Hassan Rivaz, Habib Benali
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Aging Neuroscience
Subjects:
Alzheimer’s disease
Bayesian workflow
classification
hierarchical modeling
tau-positron emission tomography (PET)
magnetic resonance imaging (MRI)
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2023.1225816/full

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https://www.frontiersin.org/articles/10.3389/fnagi.2023.1225816/full

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