Marked gut microbiota dysbiosis and increased imidazole propionate are associated with a NASH Göttingen Minipig model

Marked gut microbiota dysbiosis and increased imidazole propionate are associated with a NASH Göttingen Minipig model

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Abstract Background Gut microbiota dysbiosis is associated with the development of non-alcoholic steatohepatitis (NASH) through modulation of gut barrier, inflammation, lipid metabolism, bile acid signaling and short-chain fatty acid production. The aim of this study was to describe the impact of a...

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Bibliographic Details
Main Authors: Ditte Olsen Lützhøft, Tim Sinioja, Berit Ø. Christoffersen, Rasmus Riemer Jakobsen, Dawei Geng, Hajar Fauzan Bin Ahmad, Ellen Marie Straarup, Karen-Margrethe Pedersen, Witold Kot, Henrik Duelund Pedersen, Susanna Cirera, Tuulia Hyötyläinen, Dennis Sandris Nielsen, Axel Kornerup Hansen
Format: Article
Language:English
Published: BMC 2022-12-01
Series:BMC Microbiology
Subjects:
Hyperglucagonemia
SCFA
pH
colon microbiota
Bile acids
Imidazole propionate
Online Access:https://doi.org/10.1186/s12866-022-02704-w

Internet

https://doi.org/10.1186/s12866-022-02704-w

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