Changes in Drp1 Function and Mitochondrial Morphology Are Associated with the α-Synuclein Pathology in a Transgenic Mouse Model of Parkinson’s Disease

Changes in Drp1 Function and Mitochondrial Morphology Are Associated with the α-Synuclein Pathology in a Transgenic Mouse Model of Parkinson’s Disease

Alterations in mitochondrial function and morphology are associated with many human diseases, including cancer and neurodegenerative diseases. Mitochondrial impairment is linked to Parkinson’s disease (PD) pathogenesis, and alterations in mitochondrial dynamics are seen in PD models. In particular,...

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Bibliographic Details
Main Authors: Philipp Portz, Michael K. Lee
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Cells
Subjects:
Parkinson
mitochondria
fission
fusion
mitophagy
alpha-synuclein
Online Access:https://www.mdpi.com/2073-4409/10/4/885

Internet

https://www.mdpi.com/2073-4409/10/4/885

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