Neuroprotection afforded by prior citicoline administration in experimental brain ischemia: effects on glutamate transport

Neuroprotection afforded by prior citicoline administration in experimental brain ischemia: effects on glutamate transport

Background and purpose:: Cytidine-5′-diphosphocholine (citicoline or CDP-choline), an intermediate in the biosynthesis of phosphatidylcholine, has shown beneficial effects in a number of CNS injury models including cerebral ischemia. Citicoline is the only neuroprotectant that has proved efficacy in...

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Bibliographic Details
Main Authors: Olivia Hurtado, María A. Moro, Antonio Cárdenas, Verónica Sánchez, Paz Fernández-Tomé, Juan C. Leza, Pedro Lorenzo, Julio J. Secades, Rafael Lozano, Antoni Dávalos, José Castillo, Ignacio Lizasoain
Format: Article
Language:English
Published: Elsevier 2005-03-01
Series:Neurobiology of Disease
Subjects:
Astrocytes
ATP
Cerebral infarction
Middle cerebral artery occlusion
Neurones
OGD
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996104002426

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http://www.sciencedirect.com/science/article/pii/S0969996104002426

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