Cyclophilin D as a potential therapeutic target of liver ischemia/reperfusion injury by mediating crosstalk between apoptosis and autophagy

Cyclophilin D as a potential therapeutic target of liver ischemia/reperfusion injury by mediating crosstalk between apoptosis and autophagy

Abstract Background Liver ischemia/reperfusion (I/R) injury is a complex and multifactorial pathophysiological process. It is well recognized that the membrane permeability transition pore (mPTP) opening of mitochondria plays a crucial role in cell death after I/R injury. Cyclophilin D (CypD) is a c...

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Bibliographic Details
Main Authors: Mengjiao Yang, Zhihui Wang, Jin Xie, Md. Reyad‐ul‐Ferdous, Siying Li, Yongfeng Song
Format: Article
Language:English
Published: Wiley 2023-09-01
Series:Chronic Diseases and Translational Medicine
Subjects:
apoptosis
autophagy
cyclophilin D
ischemia/reperfusion
necrosis
reactive oxygen species
Online Access:https://doi.org/10.1002/cdt3.78

Internet

https://doi.org/10.1002/cdt3.78

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