Synthesis and application of stimulus-triggered cyclic caged oligonucleotides for gene expression regulation

Cyclically caged oligonucleotides are a distinct category of altered biomacromolecules. They are created by incorporating caged motifs into oligonucleotides and subsequently undergoing cyclization through chemical or enzymatic means. The cyclic structure of these oligonucleotides significantly affec...

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Bibliographic Details
Main Authors: Wen-Da Chen, Liang Cheng
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Tetrahedron Chem
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666951X23000177