A drug repurposing screen for whipworms informed by comparative genomics.
Hundreds of millions of people worldwide are infected with the whipworm Trichuris trichiura. Novel treatments are urgently needed as current drugs, such as albendazole, have relatively low efficacy. We have investigated whether drugs approved for other human diseases could be repurposed as novel ant...
Main Authors: | , , , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2023-09-01
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Series: | PLoS Neglected Tropical Diseases |
Online Access: | https://journals.plos.org/plosntds/article/file?id=10.1371/journal.pntd.0011205&type=printable |