Revealing the Pathogenesis of Salt-Sensitive Hypertension in Dahl Salt-Sensitive Rats through Integrated Multi-Omics Analysis

Salt-induced renal metabolism dysfunction is an important mechanism of salt-sensitive hypertension. Given that the gut-liver axis is the first hit of a high-salt diet (HSD), we aimed to identify the extra-renal mechanism from hepatic metabolism and gut microbiota, and attempted to relieve the salt-i...

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Bibliographic Details
Main Authors: Ya-nan Ou-Yang, Meng-di Yuan, Zheng-mao Yang, Zhuo Min, Yue-xin Jin, Zhong-min Tian
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Metabolites
Subjects:
Online Access:https://www.mdpi.com/2218-1989/12/11/1076