Increased Susceptibility to Pilocarpine-Induced Status Epilepticus and Reduced Latency in TRPC1/4 Double Knockout Mice

Canonical transient receptor potential channels (TRPCs) are a family of calcium-permeable cation channels. Previous studies have shown that heteromeric channels comprising TRPC1 and TRPC4 mediate epileptiform bursting in lateral septal neurons and hippocampal CA1 pyramidal neurons, suggesting that T...

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Bibliographic Details
Main Authors: Fang Zheng, Kevin D. Phelan, U Thaung Shwe
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Neurology International
Subjects:
Online Access:https://www.mdpi.com/2035-8377/15/4/95