Tracking the evolution of epialleles during neural differentiation and brain development: D-Aspartate oxidase as a model gene

Tracking the evolution of epialleles during neural differentiation and brain development: D-Aspartate oxidase as a model gene

We performed ultra-deep methylation analysis at single molecule level of the promoter region of developmentally regulated D-Aspartate oxidase (Ddo), as a model gene, during brain development and embryonic stem cell neural differentiation. Single molecule methylation analysis enabled us to establish...

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Bibliographic Details
Main Authors: Ermanno Florio, Simona Keller, Lorena Coretti, Ornella Affinito, Giovanni Scala, Francesco Errico, Annalisa Fico, Francesca Boscia, Maria Josè Sisalli, Mafalda Giovanna Reccia, Gennaro Miele, Antonella Monticelli, Antonella Scorziello, Francesca Lembo, Luca Colucci-D'Amato, Gabriella Minchiotti, Vittorio Enrico Avvedimento, Alessandro Usiello, Sergio Cocozza, Lorenzo Chiariotti
Format: Article
Language:English
Published: Taylor & Francis Group 2017-01-01
Series:Epigenetics
Subjects:
brain dna methylation
brain cells
epipolymorphism
epialleles
epigenetic dynamics
Online Access:http://dx.doi.org/10.1080/15592294.2016.1260211

Internet

http://dx.doi.org/10.1080/15592294.2016.1260211

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