Identification of TRDV-TRAJ V domains in human and mouse T-cell receptor repertoires

Identification of TRDV-TRAJ V domains in human and mouse T-cell receptor repertoires

Here, we describe the identification of two T-cell receptors (TRs) containing TRDV genes in their TRA chains, the first one in human and the second one in mouse. First, using 5’RACE on a mixed lymphocyte-tumor cell culture (MLTC), we identified TRDV1 5’-untranslated region (UTR) and complete coding...

Full description

Bibliographic Details
Main Authors: Michael Volkmar, Elham Fakhr, Stefan Zens, Alice Bury, Rienk Offringa, Jessica Gordon, Enes Huduti, Thomas Wölfel, Catherine Wölfel
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Immunology
Subjects:
T cell receptor (TR)
TCR
TRDV-TRAJ
hybrid V-domain
V-(D)-J rearrangement
TRDV1
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1286688/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1286688/full

Similar Items