N-cadherin-regulated FGFR ubiquitination and degradation control mammalian neocortical projection neuron migration

N-cadherin-regulated FGFR ubiquitination and degradation control mammalian neocortical projection neuron migration

The functions of FGF receptors (FGFRs) in early development of the cerebral cortex are well established. Their functions in the migration of neocortical projection neurons, however, are unclear. We have found that FGFRs regulate multipolar neuron orientation and the morphological change into bipolar...

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Bibliographic Details
Main Authors: Elif Kon, Elisa Calvo-Jiménez, Alexia Cossard, Youn Na, Jonathan A Cooper, Yves Jossin
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-10-01
Series:eLife
Subjects:
cerebral cortex
neuronal migration
FGFR
embryogenesis
ubiquitin
development
Online Access:https://elifesciences.org/articles/47673

Internet

https://elifesciences.org/articles/47673

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