Hydrophobic Drug/Toxin Binding Sites in Voltage-Dependent K+ and Na+ Channels
In the Nav channel family the lipophilic drugs/toxins binding sites and the presence of fenestrations in the channel pore wall are well defined and categorized. No such classification exists in the much larger Kv channel family, although certain lipophilic compounds seem to deviate from binding to w...
| Главные авторы: | , , , |
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| Формат: | Статья |
| Язык: | English |
| Опубликовано: |
Frontiers Media S.A.
2020-05-01
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| Серии: | Frontiers in Pharmacology |
| Предметы: | |
| Online-ссылка: | https://www.frontiersin.org/article/10.3389/fphar.2020.00735/full |