Development and Evaluation of Solid Lipid Nanoparticles for the Clearance of Aβ in Alzheimer’s Disease

Development and Evaluation of Solid Lipid Nanoparticles for the Clearance of Aβ in Alzheimer’s Disease

Aggregation of Amyloid-β (Aβ) leads to the formation and deposition of neurofibrillary tangles and plaques which is the main pathological hallmark of Alzheimer’s disease (AD). The bioavailability of the drugs and their capability to cross the BBB plays a crucial role in the therapeutics of AD. The p...

Full description

Bibliographic Details
Main Authors: Meghana Goravinahalli Shivananjegowda, Umme Hani, Riyaz Ali M. Osmani, Ali H. Alamri, Mohammed Ghazwani, Yahya Alhamhoom, Mohamed Rahamathulla, Sathishbabu Paranthaman, Devegowda Vishakante Gowda, Ayesha Siddiqua
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Pharmaceutics
Subjects:
drug delivery
nanotechnology
alzheimer’s disease
Amyloid-β
solid lipid nanoparticles
SHSY5Y cells
Online Access:https://www.mdpi.com/1999-4923/15/1/221

Internet

https://www.mdpi.com/1999-4923/15/1/221

Similar Items