EGF receptor inhibitors comprehensively suppress hepatitis B virus by downregulation of STAT3 phosphorylation

EGF receptor inhibitors comprehensively suppress hepatitis B virus by downregulation of STAT3 phosphorylation

Current antiviral therapy can not cure chronic hepatitis B virus (HBV) infection or eliminate the risk of hepatocellular carcinoma. The licensed epidermal growth factor receptor (EGFR) inhibitors have found to inhibit hepatitis C virus replication via downregulation of signal transducers and activat...

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Bibliographic Details
Main Authors: Chong J. Gan, Wen F. Li, Chun N. Li, Ling L. Li, Wen Y. Zhou, Xiao M. Peng
Format: Article
Language:English
Published: Elsevier 2020-07-01
Series:Biochemistry and Biophysics Reports
Subjects:
Hepatitis B virus
Antiviral therapy
Epidermal growth factor receptor inhibitor
STAT3
Covalently closed circular DNA
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580820300728

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http://www.sciencedirect.com/science/article/pii/S2405580820300728

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