Temporo-spectral imaging of intrinsic optical signals during hypoxia-induced spreading depression-like depolarization.

Spreading depression (SD) is characterized by a sustained near-complete depolarization of neurons, a massive depolarization of glia, and a negative deflection of the extracellular DC potential. These electrophysiological signs are accompanied by an intrinsic optical signal (IOS) which arises from ch...

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Bibliographic Details
Main Authors: Maria Mané, Michael Müller
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3430631?pdf=render