IGFBP1 inhibits the invasion, migration, and apoptosis of HTR-8/SVneo trophoblast cells in preeclampsia

Objective To investigate the effects and underlying mechanisms of IGFBP1 on the biological functions of trophoblasts in simulated preeclampsia. Methods IGFBP1 expression in placenta was determined by immunohistochemistry. HTR-8/SVneo cells were stimulated with/without IGFBP1-overexpression and hypox...

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Bibliographic Details
Main Authors: Xiujuan Li, Chenxi Li, Ye Wang, Jianxing Cai, Li Zhao, Zhiying Su, Huiming Ye
Format: Article
Language:English
Published: Taylor & Francis Group 2022-01-01
Series:Hypertension in Pregnancy
Subjects:
Online Access:http://dx.doi.org/10.1080/10641955.2022.2033259