Fgf4 maintains Hes7 levels critical for normal somite segmentation clock function

During vertebrate development, the presomitic mesoderm (PSM) periodically segments into somites, which will form the segmented vertebral column and associated muscle, connective tissue, and dermis. The periodicity of somitogenesis is regulated by a segmentation clock of oscillating Notch activity. H...

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Autori principali: Matthew J Anderson, Valentin Magidson, Ryoichiro Kageyama, Mark Lewandoski
Natura: Articolo
Lingua:English
Pubblicazione: eLife Sciences Publications Ltd 2020-11-01
Serie:eLife
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Accesso online:https://elifesciences.org/articles/55608