Dexmedetomidine attenuates postoperative spatial memory impairment after surgery by reducing cytochrome C

Dexmedetomidine attenuates postoperative spatial memory impairment after surgery by reducing cytochrome C

Abstract Background Anesthesia and surgery can induce perioperative neurocognitive disorders (PND). Mitochondrial dysfunction has been proposed to be one of the earliest triggering events in surgery-induced neuronal damage. Dexmedetomidine has been demonstrated to attenuate the impairment of cogniti...

Full description

Bibliographic Details
Main Authors: Lina Sun, Kun Niu, Jian Guo, Jingru Tu, Baofeng Ma, Jianxiong An
Format: Article
Language:English
Published: BMC 2023-03-01
Series:BMC Anesthesiology
Subjects:
Dexmedetomidine
Anesthesia and surgery
Mitochondrial damage
Cognitive impairment
Hippocampus
Online Access:https://doi.org/10.1186/s12871-023-02035-x

Internet

https://doi.org/10.1186/s12871-023-02035-x

Similar Items