Cells producing residual viremia during antiretroviral treatment appear to contribute to rebound viremia following interruption of treatment.

During antiretroviral therapy (ART) that suppresses HIV replication to below the limit-of-quantification, virions produced during ART can be detected at low frequencies in the plasma, termed residual viremia (RV). We hypothesized that a reservoir of HIV-infected cells actively produce and release vi...

Full description

Bibliographic Details
Main Authors: Hadega A Aamer, Jan McClure, Daisy Ko, Janine Maenza, Ann C Collier, Robert W Coombs, James I Mullins, Lisa M Frenkel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-08-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1008791