TXNIP reduces pro-proliferation effect of GLP-1 on mouse islet β cells

Objective To observe the role of thioredoxin interacting protein (TXNIP) in the proliferation of islet β cells promoted by Glucagon-like peptide 1 (GLP-1). Methods The mice were divided into db/m group and db/db group; TXNIP over-expression (Ad-TXNIP-GFP) MIN6 cells were constructed by stably tra...

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Bibliographic Details
Main Author: ZHANG Wen-ting, WANG Jin, YUE Ji-ping, JIN Wen-wen, ZHANG Zhi-nan, JIAO Xiang-ying
Format: Article
Language:zho
Published: Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College. 2020-08-01
Series:Jichu yixue yu linchuang
Subjects:
Online Access:http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/a190822.pdf