Cloning and comparative analyses of the zebrafish Ugt repertoire reveal its evolutionary diversity.

UDP-glucuronosyltransferases (Ugts) are a supergene family of phase II drug-metabolizing enzymes that catalyze the conjugation of numerous hydrophobic small molecules with the UDP-glucuronic acid, converting them into hydrophilic molecules. Here, we report the identification and cloning of the compl...

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Bibliographic Details
Main Authors: Haiyan Huang, Qiang Wu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2819257?pdf=render