Role of pharmacogenetic factors in the development of side effects of methotrexate in the treatment of malignant tumors: A review

Methotrexate (MTX) is one of the main chemotherapeutic agents that has determined the high effectiveness of protocols for the treatment of acute lymphoblastic leukemia and non-Hodgkin lymphomas. The reverse side of the high anti-tumor activity of MTX is the adverse reactions, which require accompany...

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Bibliographic Details
Main Authors: Timur T. Valiev, Vera V. Semenova, Anna Yu. Ikonnikova, Alisa A. Petrova, Tatiana S. Belysheva, Tatiana V. Nasedkina
Format: Article
Language:Russian
Published: IP Habib O.N. 2021-12-01
Series:Современная онкология
Subjects:
Online Access:https://modernonco.orscience.ru/1815-1434/article/viewFile/79133/pdf