Albumin/Thiacalix[4]arene Nanoparticles as Potential Therapeutic Systems: Role of the Macrocycle for Stabilization of Monomeric Protein and Self-Assembly with Ciprofloxacin

Albumin/Thiacalix[4]arene Nanoparticles as Potential Therapeutic Systems: Role of the Macrocycle for Stabilization of Monomeric Protein and Self-Assembly with Ciprofloxacin

The therapeutic application of serum albumin is determined by the relative content of the monomeric form compared to dimers, tetramers, hexamers, etc. In this paper, we propose and develop an approach to synthesize the <i>cone</i> stereoisomer of <i>p-tert</i>-butylthiacalix[...

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Bibliographic Details
Main Authors: Luidmila Yakimova, Aisylu Kunafina, Olga Mostovaya, Pavel Padnya, Timur Mukhametzyanov, Alexandra Voloshina, Konstantin Petrov, Artur Boldyrev, Ivan Stoikov
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:International Journal of Molecular Sciences
Subjects:
sulfobetaines
thiacalixarene
self-assembly
bovine serum albumin
ciprofloxacin
Online Access:https://www.mdpi.com/1422-0067/23/17/10040

Internet

https://www.mdpi.com/1422-0067/23/17/10040

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