The Impact of Cytogenetic Aberrations in the Clonal Evolution of Chronic Myeloid Leukemia: A Single-Center Experience Among 450 Turkish Patients (Cohort Study)

The Impact of Cytogenetic Aberrations in the Clonal Evolution of Chronic Myeloid Leukemia: A Single-Center Experience Among 450 Turkish Patients (Cohort Study)

Objective: Objective: Chronic myeloid leukemia (CML) is a clonal hematologic disorder characterized by t(9;22) translocation, in which cytogenetic aberrations can occur in Ph(+) and (-) clones. These aberrations develop due to clonal evolution as well as treatment and they have prognostic significan...

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Bibliographic Details
Main Authors: Sevgi Işık, Gülçin Günden, Hava Üsküdar Teke, Olga Meltem Akay, Nur Oğuz Davutoğlu, Vahap Aslan, Mustafa Karagülle, Hülya Özen, Oğuz Çilingir, Sevilhan Artan, Beyhan Durak Aras
Format: Article
Language:English
Published: Galenos Publishing House 2022-11-01
Series:Turkish Journal of Hematology
Subjects:
chronic myeloid leukemia
cytogenetics
clonal evolution
prognostic aberrations
philadelphia chromosome
Online Access:https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tjh&un=TJH-22623

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https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tjh&un=TJH-22623

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