Genomic Context Differs Between Human Dilated Cardiomyopathy and Hypertrophic Cardiomyopathy

Genomic Context Differs Between Human Dilated Cardiomyopathy and Hypertrophic Cardiomyopathy

Background Inherited cardiomyopathies display variable penetrance and expression, and a component of phenotypic variation is genetically determined. To evaluate the genetic contribution to this variable expression, we compared protein coding variation in the genomes of those with hypertrophic cardio...

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מידע ביבליוגרפי
Main Authors: Megan J. Puckelwartz, Lorenzo L. Pesce, Lisa M. Dellefave‐Castillo, Matthew T. Wheeler, Tess D. Pottinger, Avery C. Robinson, Samuel D. Kearns, Anthony M. Gacita, Zachary J. Schoppen, Wenyu Pan, Gene Kim, Jane E. Wilcox, Allen S. Anderson, Euan A. Ashley, Sharlene M. Day, Thomas Cappola, Gerald W. Dorn, Elizabeth M. McNally
פורמט: Article
שפה:English
יצא לאור: Wiley 2021-04-01
סדרה:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
נושאים:
dilated cardiomyopathy
hypertrophic cardiomyopathy
modifier genes
variable expressivity
variant burden
גישה מקוונת:https://www.ahajournals.org/doi/10.1161/JAHA.120.019944

אינטרנט

https://www.ahajournals.org/doi/10.1161/JAHA.120.019944

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