The desmosomal armadillo protein plakoglobin regulates prostate cancer cell adhesion and motility through vitronectin-dependent Src signaling.

The desmosomal armadillo protein plakoglobin regulates prostate cancer cell adhesion and motility through vitronectin-dependent Src signaling.

Plakoglobin (PG) is an armadillo protein that associates with both classic and desmosomal cadherins, but is primarily concentrated in mature desmosomes in epithelia. While reduced levels of PG have been reported in localized and hormone refractory prostate tumors, the functional significance of thes...

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Bibliographic Details
Main Authors: Carrie A Franzen, Viktor Todorović, Bhushan V Desai, Salida Mirzoeva, Ximing J Yang, Kathleen J Green, Jill C Pelling
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3408445?pdf=render

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http://europepmc.org/articles/PMC3408445?pdf=render

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