Deregulation of lysophosphatidic acid metabolism in oral cancer promotes cell migration via the up-regulation of COX-2

Oral squamous cell carcinoma (OSCC) is the sixth most common cancer worldwide and accounts for 300,000 new cases yearly. The five-year survival rate is approximately 50% and the major challenges to improving patient prognosis include late presentation, treatment resistance, second primary tumours an...

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Bibliographic Details
Main Authors: Mariati Abdul Rahman, May Leng Tan, Steven P. Johnson, Robert J. Hollows, Wen Lin Chai, Jason P. Mansell, Lee Fah Yap, Ian C. Paterson
Format: Article
Language:English
Published: PeerJ Inc. 2020-11-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/10328.pdf