RASAL2 promotes tumor progression through LATS2/YAP1 axis of hippo signaling pathway in colorectal cancer

RASAL2 promotes tumor progression through LATS2/YAP1 axis of hippo signaling pathway in colorectal cancer

Abstract Background Patients with colorectal cancer (CRC) have a high incidence of regional and distant metastases. Although metastasis is the main cause of CRC-related death, its molecular mechanisms remain largely unknown. Methods Using array-CGH and expression microarray analyses, changes in DNA...

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Bibliographic Details
Main Authors: Yi Pan, Joanna Hung Man Tong, Raymond Wai Ming Lung, Wei Kang, Johnny Sheung Him Kwan, Wing Po Chak, Ka Yee Tin, Lau Ying Chung, Feng Wu, Simon Siu Man Ng, Tony Wing Chung Mak, Jun Yu, Kwok Wai Lo, Anthony Wing Hung Chan, Ka Fai To
Format: Article
Language:English
Published: BMC 2018-07-01
Series:Molecular Cancer
Subjects:
RASAL2
Hippo
LATS2
YAP1
Colorectal cancer
Online Access:http://link.springer.com/article/10.1186/s12943-018-0853-6

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http://link.springer.com/article/10.1186/s12943-018-0853-6

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