Protective effect of ischaemic postconditioning combined with nicorandil on myocardial ischaemia‒reperfusion injury in diabetic rats

Protective effect of ischaemic postconditioning combined with nicorandil on myocardial ischaemia‒reperfusion injury in diabetic rats

Abstract Background The diabetic heart exhibits a high sensitivity to ischaemia/reperfusion (I/R) injury. Diabetes mellitus (DM) can affect the efficacy of cardioprotective interventions and reduce the therapeutic potential of existing treatment options. This study aimed to investigate the feasibili...

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Detaylı Bibliyografya
Asıl Yazarlar: Zongyi Xia, Bing Chen, Chi Zhou, Yitian Wang, Jinyang Ren, Xujin Yao, Yifan Yang, Qi Wan, Zhexun Lian
Materyal Türü: Makale
Dil:English
Baskı/Yayın Bilgisi: BMC 2022-12-01
Seri Bilgileri:BMC Cardiovascular Disorders
Konular:
Ischaemia postconditioning
Myocardial ischaemia‒reperfusion injury
Nicorandil
PI3K/Akt signalling pathway
Type 2 diabetes mellitus
Online Erişim:https://doi.org/10.1186/s12872-022-02967-1

Internet

https://doi.org/10.1186/s12872-022-02967-1

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