Expression of HIF-1α and markers of angiogenesis and metabolic adaptation in molecular subtypes of breast cancer

Abstract Hypoxic zones exist in solid tumors, where oxygen levels are significantly lower than in normal tissues. Hypoxia makes chemo-radiation therapeutics less effective and renders the metastatic potential more favorable. Emerging research has found that the transcriptional expression of hypoxia-...

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Bibliographic Details
Main Authors: Muzamil Farooq, Gh. Rasool Bhat, Syed Besina, Natasha Thakur, Sheikh Zahoor, Rafiq A. Rather, Ifra Mushtaq, Sadaf Dar, Bilal Rah, Ajaz A. Bhat, Muzafar A. Macha, Dil Afroze
Format: Article
Language:English
Published: BMC 2023-01-01
Series:Translational Medicine Communications
Online Access:https://doi.org/10.1186/s41231-023-00135-x