Rhei Undulati Rhizoma attenuates memory decline and reduces amyloid-β induced neuritic dystrophy in 5xFAD mouse

Rhei Undulati Rhizoma attenuates memory decline and reduces amyloid-β induced neuritic dystrophy in 5xFAD mouse

Abstract Background Alzheimer's disease (AD) is a common type of dementia characterized by amyloid-β (Aβ) accumulation, lysosomal dysfunction, and tau hyperphosphorylation, leading to neurite dystrophy and memory loss. This study aimed to investigate whether Rhei Undulati Rhizoma (RUR), which h...

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Bibliographic Details
Main Authors: Seungmin Lee, In Gyoung Ju, Hyeyoon Eo, Jin Hee Kim, Yujin Choi, Myung Sook Oh
Format: Article
Language:English
Published: BMC 2024-07-01
Series:Chinese Medicine
Subjects:
Rhei Undulati Rhizoma
Amyloid-β
Dystrophic neurites
β-Site amyloid precursor protein cleaving enzyme-1
Tau hyperphosphorylation
Online Access:https://doi.org/10.1186/s13020-024-00966-2

Internet

https://doi.org/10.1186/s13020-024-00966-2

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