Modified gemcitabine, S-1, and leucovorin combination for patients with newly diagnosed locally advanced or metastatic pancreatic adenocarcinoma: A multi-center retrospective study in Taiwan.

<h4>Background</h4>In pancreatic cancer, toxicities associated with current chemotherapeutic regimens remain concerning. A modified combination of gemcitabine, S-1, and leucovorin (GSL) was used as the first-line treatment for newly diagnosed locally advanced or metastatic pancreatic ade...

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Bibliographic Details
Main Authors: Chia-Yu Chen, Shih-Hsin Liang, Yung-Yeh Su, Nai-Jung Chiang, Hui-Ching Wang, Chang-Fang Chiu, Li-Tzong Chen, Li-Yuan Bai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0244487