A Literature Review of Changes in Phase II Drug-Metabolizing Enzyme and Drug Transporter Expression during Pregnancy

A Literature Review of Changes in Phase II Drug-Metabolizing Enzyme and Drug Transporter Expression during Pregnancy

The purpose of this literature review is to comprehensively summarize changes in the expression of phase II drug-metabolizing enzymes and drug transporters in both the pregnant woman and the placenta. Using PubMed<sup>®</sup>, a systematic search was conducted to identify literature rele...

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Bibliographic Details
Main Authors: Christine Gong, Lynn N. Bertagnolli, David W. Boulton, Paola Coppola
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Pharmaceutics
Subjects:
pregnancy
placenta
gestational change
phase II enzyme
drug transporter
physiologically based pharmacokinetic (PBPK) modeling
Online Access:https://www.mdpi.com/1999-4923/15/11/2624

Internet

https://www.mdpi.com/1999-4923/15/11/2624

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