Synthesis of Novel Glycerol-Derived 1,2,3-Triazoles and Evaluation of Their Fungicide, Phytotoxic and Cytotoxic Activities

Synthesis of Novel Glycerol-Derived 1,2,3-Triazoles and Evaluation of Their Fungicide, Phytotoxic and Cytotoxic Activities

The synthesis of a series of 1,2,3-triazoles using glycerol as starting material is described. The key step in the preparation of these triazolic derivatives is the copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC), also known as click reaction, between 4-(azidomethyl)-2,2-dimethyl-1,3-dioxolan...

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Bibliographic Details
Main Authors: Adilson Vidal Costa, Marcos Vinicius Lacerda de Oliveira, Roberta Tristão Pinto, Luiza Carvalheira Moreira, Ediellen Mayara Corrêa Gomes, Thammyres de Assis Alves, Patrícia Fontes Pinheiro, Vagner Tebaldi de Queiroz, Larissa Fonseca Andrade Vieira, Robson Ricardo Teixeira, Waldir Cintra de Jesus Júnior
Format: Article
Language:English
Published: MDPI AG 2017-10-01
Series:Molecules
Subjects:
glycerol
1,2,3-triazoles
fungicide
cytotoxic activity
click chemistry
Online Access:https://www.mdpi.com/1420-3049/22/10/1666

Internet

https://www.mdpi.com/1420-3049/22/10/1666

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