A Stable Cell Line Expressing Clustered AChR: A Novel Cell-Based Assay for Anti-AChR Antibody Detection in Myasthenia Gravis

A Stable Cell Line Expressing Clustered AChR: A Novel Cell-Based Assay for Anti-AChR Antibody Detection in Myasthenia Gravis

Cell-based assays (CBAs) and radioimmunoprecipitation assay (RIPA) are the most sensitive methods for identifying anti-acetylcholine receptor (AChR) antibody in myasthenia gravis (MG). But CBAs are limited in clinical practice by transient transfection. We established a stable cell line (KL525) expr...

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Bibliografiska uppgifter
Huvudupphovsmän: Yu Cai, Lu Han, Desheng Zhu, Jing Peng, Jianping Li, Jie Ding, Jiaying Luo, Ronghua Hong, Kan Wang, Wenbin Wan, Chong Xie, Xiajun Zhou, Ying Zhang, Yong Hao, Yangtai Guan
Materialtyp: Artikel
Språk:English
Publicerad: Frontiers Media S.A. 2021-07-01
Serie:Frontiers in Immunology
Ämnen:
myasthenia gravis
neuromuscular junction
clustered acetylcholine receptor
cell-based assay (CBA)
stable cell line
Länkar:https://www.frontiersin.org/articles/10.3389/fimmu.2021.666046/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.666046/full

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