Quantitative Structure-Activity Relationship Studies of 4-Imidazolyl- 1,4-dihydropyridines as Calcium Channel Blockers

Objective(s): The structure- activity relationship of a series of 36 molecules, showing L-type calcium channel blocking was studied using a QSAR (quantitative structure–activity relationship) method. Materials and Methods: Structures were optimized by the semi-empirical AM1 quantum-chemical method w...

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Bibliographic Details
Main Authors: Farzin Hadizadeh, Saadat Vahdani, Mehrnaz Jafarpour
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2013-08-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Online Access:http://ijbms.mums.ac.ir/pdf_1349_f60202f21add9698ced30dc8da8aefb2.html