Mitochondrial antioxidant elamipretide improves learning and memory impairment induced by chronic sleep deprivation in mice

Mitochondrial antioxidant elamipretide improves learning and memory impairment induced by chronic sleep deprivation in mice

Abstract Background The inflammation and synaptic dysfunction induced by mitochondrial dysfunction play essential roles in the learning and memory impairment associated with sleep dysfunction. Elamipretide (SS‐31), a novel mitochondrion‐targeted antioxidant, was proven to improve mitochondrial dysfu...

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Bibliographic Details
Main Authors: Yue‐Ming Zhang, Ya‐Tao Wang, Ru‐Meng Wei, Xue‐Yan Li, Bao‐Ling Luo, Jing‐Ya Zhang, Kai‐Xuan Zhang, Shi‐Kun Fang, Xue‐Chun Liu, Gui‐Hai Chen
Format: Article
Language:English
Published: Wiley 2024-05-01
Series:Brain and Behavior
Subjects:
inflammatory
learning and memory
mitochondrial dysfunction
SIRT1
SS‐31
synaptic proteins
Online Access:https://doi.org/10.1002/brb3.3508

Internet

https://doi.org/10.1002/brb3.3508

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