Lysyl oxidase expression is associated with inferior outcome and Extramedullary disease of acute myeloid leukemia

Lysyl oxidase expression is associated with inferior outcome and Extramedullary disease of acute myeloid leukemia

Abstract Background Lysyl oxidase (LOX) has been described as necessary for premetastatic niche formation in epithelium-derived malignancies and its expression level therefore correlates with risk of metastatic disease and overall survival. However, its role in acute myeloid leukemia (AML) has not b...

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Bibliographic Details
Main Authors: Desiree Kunadt, Michael Kramer, Claudia Dill, Heidi Altmann, Lisa Wagenführ, Brigitte Mohr, Christian Thiede, Christoph Röllig, Johannes Schetelig, Martin Bornhäuser, Markus Schaich, Friedrich Stölzel
Format: Article
Language:English
Published: BMC 2020-06-01
Series:Biomarker Research
Subjects:
Acute myeloid leukemia
Lysyl oxidase
Extramedullary AML
Survival
Prognosis
Online Access:http://link.springer.com/article/10.1186/s40364-020-00200-9

Internet

http://link.springer.com/article/10.1186/s40364-020-00200-9

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