Intravesical Instillation of Norketamine, a Ketamine Metabolite, and Induced Bladder Functional Changes in Rats

This study aimed to determine the mechanism of ketamine-induced cystitis without metabolism. A total of 24 adult male Sprague-Dawley rats were separated into control, ketamine, and norketamine groups. To induce cystitis, rats in the ketamine and norketamine groups were treated with intravesical inst...

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Bibliographic Details
Main Authors: Chung-Hsin Yeh, Bo-He Chen, Xiao-Wen Tseng, Chun-Hou Liao, Wei-Kung Tsai, Han-Sun Chiang, Yi-No Wu
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Toxics
Subjects:
Online Access:https://www.mdpi.com/2305-6304/9/7/154