High-performance liquid chromatography local reference ranges of hemoglobin fractions (HbA, HbA2, and HbF) in detection of hemoglobinopathies in western Kenya

Abstract Background Western Kenya, being a malaria-endemic region, has a high prevalence of hemoglobinopathies mostly sickle cell and thalassemia. The hemoglobin fractions or variants, HbA, HbA2, and HbF, serve as biomarkers for the detection of hemoglobinopathies and are commonly used in laboratory...

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Bibliographic Details
Main Authors: Benard Mutua, Rose Chelangat, Barasa Mustafa, Tom Were, Julie Makani, George Sowayi, Patrick Okoth
Format: Article
Language:English
Published: SpringerOpen 2022-12-01
Series:The Egyptian Journal of Internal Medicine
Online Access:https://doi.org/10.1186/s43162-022-00187-9