Improving the Angiogenic Potential of EPCs via Engineering with Synthetic Modified mRNAs

The application of endothelial progenitor cells (EPCs) for the revascularization of ischemic tissues, such as after myocardial infarction, stroke, and acute limb ischemia, has a huge clinical potential. However, the low retention and engraftment of EPCs as well as the poor survival of migrated stem...

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Bibliographic Details
Main Authors: Heidrun Steinle, Sonia Golombek, Andreas Behring, Christian Schlensak, Hans Peter Wendel, Meltem Avci-Adali
Format: Article
Language:English
Published: Elsevier 2018-12-01
Series:Molecular Therapy: Nucleic Acids
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253118302440