Improving the Angiogenic Potential of EPCs via Engineering with Synthetic Modified mRNAs
The application of endothelial progenitor cells (EPCs) for the revascularization of ischemic tissues, such as after myocardial infarction, stroke, and acute limb ischemia, has a huge clinical potential. However, the low retention and engraftment of EPCs as well as the poor survival of migrated stem...
Main Authors: | Heidrun Steinle, Sonia Golombek, Andreas Behring, Christian Schlensak, Hans Peter Wendel, Meltem Avci-Adali |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2018-12-01
|
Series: | Molecular Therapy: Nucleic Acids |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2162253118302440 |
Similar Items
-
Generation of iPSCs by Nonintegrative RNA-Based Reprogramming Techniques: Benefits of Self-Replicating RNA versus Synthetic mRNA
by: Heidrun Steinle, et al.
Published: (2019-01-01) -
Intradermal Delivery of Synthetic mRNA Using Hollow Microneedles for Efficient and Rapid Production of Exogenous Proteins in Skin
by: Sonia Golombek, et al.
Published: (2018-06-01) -
Blood-Contacting Biomaterials: In Vitro Evaluation of the Hemocompatibility
by: Marbod Weber, et al.
Published: (2018-07-01) -
Efficient reduction of synthetic mRNA induced immune activation by simultaneous delivery of B18R encoding mRNA
by: Tatjana Michel, et al.
Published: (2019-05-01) -
Potential capacity of aptamers to trigger immune activation in human blood.
by: Meltem Avci-Adali, et al.
Published: (2013-01-01)