A Novel ENU-Induced Mutation in Myo6 Causes Vestibular Dysfunction and Deafness.

A Novel ENU-Induced Mutation in Myo6 Causes Vestibular Dysfunction and Deafness.

Mouse N-ethyl-N-nitrosourea (ENU) mutagenesis has generated many useful animal models for human diseases. Here we describe the identification of a novel ENU-induced mouse mutant strain Turner (Tur) that displays circling and headtossing behavior and progressive hearing loss. Tur/Tur homozygous anima...

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Bibliographic Details
Main Authors: Elaine Y M Wong, Chelsea Y Xu, Manisha Brahmachary, Pin-Xian Xu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4865150?pdf=render

Internet

http://europepmc.org/articles/PMC4865150?pdf=render

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