Autosomal dominant cerebellar ataxias: Imaging biomarkers with high effect sizes
Objective: As gene-based therapies may soon arise for patients with spinocerebellar ataxia (SCA), there is a critical need to identify biomarkers of disease progression with effect sizes greater than clinical scores, enabling trials with smaller sample sizes. Methods: We enrolled a unique cohort of...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2018-01-01
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Series: | NeuroImage: Clinical |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2213158218301943 |