Age-dependent evolution of the yeast protein interaction network suggests a limited role of gene duplication and divergence.

Proteins interact in complex protein-protein interaction (PPI) networks whose topological properties-such as scale-free topology, hierarchical modularity, and dissortativity-have suggested models of network evolution. Currently preferred models invoke preferential attachment or gene duplication and...

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Bibliographic Details
Main Authors: Wan Kyu Kim, Edward M Marcotte
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-11-01
Series:PLoS Computational Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19043579/?tool=EBI