Phosphodiesterase 10A (PDE10A): Regulator of Dopamine Agonist-Induced Gene Expression in the Striatum

Phosphodiesterase 10A (PDE10A): Regulator of Dopamine Agonist-Induced Gene Expression in the Striatum

Dopamine and other neurotransmitters have the potential to induce neuroplasticity in the striatum via gene regulation. Dopamine receptor-mediated gene regulation relies on second messenger cascades that involve cyclic nucleotides to relay signaling from the synapse to the nucleus. Phosphodiesterases...

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Bibliographic Details
Main Authors: Ryan Bonate, Gabriela Kurek, Michael Hrabak, Santanna Patterson, Fernando Padovan-Neto, Anthony R. West, Heinz Steiner
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Cells
Subjects:
dopamine
L-DOPA
cocaine
striatum
phosphodiesterase
cyclic nucleotide
Online Access:https://www.mdpi.com/2073-4409/11/14/2214

Internet

https://www.mdpi.com/2073-4409/11/14/2214

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