A Combination of Culture Conditions and Gene Expression Analysis Can Be Used to Investigate and Predict hES Cell Differentiation Potential towards Male Gonadal Cells.

Human embryonic stem cell differentiation towards various cell types belonging to ecto-, endo- and mesodermal cell lineages has been demonstrated, with high efficiency rates using standardized differentiation protocols. However, germ cell differentiation from human embryonic stem cells has been very...

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Bibliographic Details
Main Authors: Kristín Rós Kjartansdóttir, Ahmed Reda, Sarita Panula, Kelly Day, Kjell Hultenby, Olle Söder, Outi Hovatta, Jan-Bernd Stukenborg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4667967?pdf=render